BIOMOLECULAR INTERACTIONS IN CLINICAL AND MOLECULAR CELL BIOLOGY

INTRODUCTION (Course objectives)

This certificate course of Biochemistry, the students will learn the principles governing the interactions of individual molecules, and how those same princi- ples apply at the scale of cells and organisms. This certificate course is led by Asutosh College faculty of Biochemistry and features:

  • detailed illustrations of concepts on fundamentals of biomolecules and their interactions in human body.
  • analytical methods and tools to investigate the biomolecular interactions.
  • clinical application of the biomolecular interactions with respect to hu- man diseases.

Course Benefits

At the end of this six-month certificate course, the students will:

  1. Get extensive exposure to theory and experimental aspects of modern bio- chemistry as well as clinical aspects of modern biology.
  2. Develop basic and fundamental ideas about the major biomolecules in human body.
  3. Generate birds eye view about the ongoing biochemical interactions and physiological role of the biomolecules.
  4. Yield knowledge about the various cellular processes at the molecular and genetic level.
  5. Acquire perception regarding the analytical tools and methods used to study the biochemical processes.
  6. Be able to gain insight into the clinical aspects of biochemistry and ap- plications in diagnosis of human diseases and pathology.

N.B. They will be encouraged to participate in the departmental seminars or webinars, and other departmental scientific activities.

Course Eligibility:

Applicants should have qualified Higher Secondary exami- nation

Course Duration:

Six-months

Course Design:

MODULE 1

Fundamentals in Biochemistry

Structural-functional analysis of basic biomolecules: Car- bohydrate, Protein, Lipid and Nucleic Acid.

Enzymology:   Characteristics,   classification,   functions, purification, mechanism and properties of action.

Nutritional role of vitamins and minerals. Nutritional Disorders.
Practical/ Online tutorial

  1. Estimation of vitamin C from fruit juice.
  2. Estimation of calcium from milk.

MODULE 2

Cell and Mole- cular Biology

Basic idea of prokaryotic and eukaryotic cell, concept of cell cycle, cell death, senescence. Introduction to cancer biology.

Tools and techniques of advanced molecular biology, DNA fingerprinting, chromosome analysis.

Applications of genetic engineering and recombinant DNA technology in medicine, forensic studies, archaeol- ogy, agriculture and industry.

Introduction to immunology and vaccine development Practical/ Online tutorial

  1. Micrographs of cell, cellular components
  2. Microscopic representation of plant, animal and bacter- ial cell.

MODULE 3

Analytical and Clinical Bio- chemistry

Clinical significance of blood glucose variations: Dia- betes mellitus

Cardiovascular diseases and tests related to that. Lipoproteins: Composition, functions, significance.
Significance of liver function test, renal function test and urine analysis.

Practical/ Online tutorial

  1. Collection, separation and storage of blood.
  2. Estimation of blood glucose and study of lipid profile

Note: Instrumentation related to all the experiments will be demonstrated online during the course.